ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025
One-year post-discharge health-related quality of life in digestive and oncology patients: a three-group comparison by nutritional status and care.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeWe evaluated changes in health-related quality of life (HRQoL) twelve months after admission among three groups of patients with digestive and oncological pathologies by nutritional status and nutritional intervention. We also sought to identify factors influencing those changes, taking into account the patients' baseline status.
methodsThis pragmatic effectiveness trial study comprised 619 hospitalized patients who completed HRQoL instruments on admission and twelve months later. Of these, 365 were classed as non-malnourished and 254 as malnourished (of whom 59 underwent nutritional intervention). Sociodemographic and clinical data were gathered. Patients completed the Short-Form 36; the EuroQol generic health-related quality of life questionnaire and the Barthel Index. Descriptive, univariate and multivariate linear regression models were applied to identify factors associated with changes in HRQoL.
resultsParticipants had a mean age of 63.5 years; 61.6% were male. Malnourished patients showed significant improvement in mental, social and physical components at the change. In the multivariate analysis, several variables affected the HRQoL of hospitalized patients one year after admission, such as level of malnutrition, pathology on admission, gender, age, Charlson Comorbidity Index, number of drugs prescribed, length of stay or surgical intervention. The nutritional intervention provided during the days of admission was not found to be associated with better HRQoL, except for role physical and body pain.
conclusionIdentifying the factors influencing changes in HRQoL amongst patients one year after their admission could help determine how important it is to improve these factors, when possible, for example through nutritional intervention prior to admission for surgery.
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