Evidence map›Paper›PMID 41452498›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Latent class analysis of quality of life among patients with Kashin-Beck disease and its association with health literacy and social support.

Haoyu Du, Ying Liu, Songyao Zhang, Fang Qi, Chenxi Wang, Jiaxin Li, Jun Yu

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Core symptoms in patients with colorectal cancer receiving chemotherapy: a network analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haoyu DuNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China.
Ying LiuNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China.
Songyao ZhangNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China.
Fang QiNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China.
Chenxi WangNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China.
Jiaxin LiNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China.
Jun YuNHC Key Laboratory of Etiology and Epidemiology, Harbin Medical University, No. 157, Health Care Road, Nangang District, Harbin, 150081, China. 6yujun@126.com.

Funding

National Key Research and Development Program of China 2022YFC2503101National Natural Science Foundation of China No.82473744
6 · The paper itself

Abstract

purposeKashin-Beck disease (KBD) is a chronic, deformative disorder that significantly reduces quality of life (QoL), yet the internal heterogeneity of QoL among individuals with KBD remains unclear. This study applied latent class analysis (LCA) to identify distinct subgroups of QoL. It explored their associations with health literacy and social support, aiming to provide evidence for improving QoL among people affected by KBD.

methodsA cross-sectional survey was conducted among 485 adult patients diagnosed with KBD in Mishan City, Heilongjiang Province, using a cluster sampling method. Data were collected through structured questionnaires, including the EQ-5D-5 L, a health literacy scale, and a social support scale. Using the scores of the five EQ-5D-5 L dimensions as input variables, LCA was performed to identify the optimal number of subgroups. Multivariable logistic regression was then applied to examine factors associated with subgroup membership.

resultsThe QoL among patients with KBD was categorized into three latent classes: a well-adapted group (66.4%), a moderately restricted group (20.2%), and a severely impaired group (13.4%). Significant differences were observed among the groups in terms of health literacy, social support, annual household income, education level, type of medical insurance, and the frequency of dairy and egg consumption in the past seven days. These factors were significantly associated with the distribution of QoL classes.

conclusionIncome, education level, type of medical insurance, frequency of dairy and egg consumption, social support, and health literacy significantly influence the QoL of patients with KBD.

Indexed as

Health LiteracyKashin-Beck DiseaseQuality of LifeSocial SupportAdultAgedChinaCross-Sectional StudiesDairy ProductsDietEducational StatusEggsEndemic DiseasesFemaleHumansIncomeHealth literacyKashin–Beck diseaseLatent class analysisQuality of lifeSocial support

Identifiers

PMID41452498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.