Evidence map›Paper›PMID 41452444›Full record

ReviewOral and maxillofacial surgery2025

Tongue cancer in pregnancy: challenges and outcomes. A case series and review of the literature.

Ahmed Abdallah, Shadi Awny, Islam H Metwally, Ahmed M Eid, Reem Ayman, Randa Abdelaal, Ransy Elhadidy, Mariam Tarek, Omar Hamdy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Oral and maxillofacial surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ahmed AbdallahSurgical oncology department, Oncology Center, Mansoura University, Mansoura, Egypt.
Shadi AwnySurgical oncology department, Oncology Center, Mansoura University, Mansoura, Egypt.
Islam H MetwallySurgical oncology department, Oncology Center, Mansoura University, Mansoura, Egypt.
Ahmed M EidSurgical oncology department, Oncology Center, Mansoura University, Mansoura, Egypt.
Reem AymanInterns, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt.
Randa AbdelaalInterns, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt.
Ransy ElhadidyInterns, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt.
Mariam TarekInterns, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt.
Omar HamdySurgical oncology department, Oncology Center, Mansoura University, Mansoura, Egypt. omarhamdy@mans.edu.eg.ORCID http://orcid.org/0000-0002-2924-4207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo highlight the management of tongue cancer during pregnancy and provide a reference for all related specialties. STUDY

designA case series of tongue cancer patients diagnosed during pregnancy. In addition, a PubMed Search and an analysis of the clinical, pathological, therapeutic, and oncological outcomes of all reported cases in the literature were performed.

resultsFifty-four patients (including three from our center) were included in the study. The mean age at diagnosis was 30.94 years, and the median gestational age at diagnosis was 22 weeks. Overall, 62.5% of patients had T1-2 disease, and 56.2% were node-negative. In 40 events (72.7%), treatment was initiated during pregnancy, where upfront surgery was performed in 24 events (43.6%). Recurrence was reported in 16 events (29.1%), with a median interval to recurrence of 4.5 months (range: 1-24 months). Although maternal outcomes were poor, with 14 (25.9%) mortality, none died from the disease during pregnancy. The fetal outcomes were acceptable, with 42 (76.4%) healthy babies delivered.

conclusionTongue cancer in pregnancy is a challenging clinical scenario that requires a case-by-case strategy within a multidisciplinary approach. Different treatment modalities are safe during pregnancy if appropriate precautions are taken. Despite the poor maternal outcome, the fetal outcomes are acceptable.

Indexed as

Pregnancy Complications, NeoplasticTongue NeoplasmsAdultFemaleHumansNeoplasm Recurrence, LocalNeoplasm StagingPregnancyPregnancy OutcomeChemotherapyFetalMaternalOral cancersPregnancyRadiotherapyTongue

Identifiers

PMID41452444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.