Evidence map›Paper›PMID 41452309›Full record

SynthesisAmerican journal of preventive medicine2026

Effectiveness of Youth Tobacco Prevention Ads: Meta-Analysis of a Decade's Worth of Copy-Testing Data.

Xiaoquan Zhao, Emily B Peterson, Megan Vigorita, Merrybelle Guo

Abstract readMeta-Analysis
In one paragraph

Synthesis in American journal of preventive medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoquan ZhaoDepartment of Communication, George Mason University, Fairfax, Virginia. Electronic address: xzhao3@gmu.edu.
Emily B PetersonCenter for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, Maryland.
Megan VigoritaCenter for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, Maryland.
Merrybelle GuoCenter for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, Maryland.

Funding

Intramural FDA HHS FD999999
6 · The paper itself

Abstract

introductionThe U.S. Food and Drug Administration has launched multiple large-scale youth tobacco prevention campaigns since 2014. Prior to launching campaigns, the U.S. Food and Drug Administration conducts copy-testing studies with youth aged 12-17 years using an experimental design (ad exposure versus no ad control) to evaluate potential ad effects on 4 outcome measures: attitudes toward tobacco use and beliefs about negative health consequences, harmful and potentially harmful constituents, and addiction.

methodsA series of meta-analyses examined the difference between exposure and control groups for each of the 4 outcome measures across 10 copy-testing studies conducted from 2013 to 2020. Potential heterogeneity in these differences was explored by campaign, tobacco product, audience characteristic, and message theme. Analysis was performed in 2024.

resultsA total of 42 ads were included in the analysis. The average effect size (Hedge's g) across all ads was 0.446 (95% CI=0.312, 0.581) for attitude, 0.319 (95% CI=0.155, 0.483) for negative health consequence beliefs, 0.246 (95% CI=0.057, 0.436) for harmful and potentially harmful constituent beliefs, and 0.347 (95% CI=0.254, 0.441) for addiction beliefs. Larger effect sizes were observed for electronic cigarette ads than for ads for other products. Ads featuring harmful and potentially harmful constituent and addiction themes generated larger effect sizes on their respective targeted beliefs than ads that did not feature these themes.

conclusionsFindings of this study provide evidence that ads from the U.S. Food and Drug Administration's tobacco prevention campaigns have the potential to positively influence relevant beliefs and attitudes among their intended youth audiences. Patterns of variation in effect sizes largely support the success of belief targeting in campaign development.

Indexed as

AdvertisingHealth PromotionSmoking PreventionAdolescentChildHealth Knowledge, Attitudes, PracticeHumansTobacco ProductsUnited StatesUnited States Food and Drug Administration

Identifiers

PMID41452309
PMCPMC13138001

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.