Evidence map›Paper›PMID 41452204›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2026

Loss to Follow-Up and Visit Nonadherence in an HIV Incidence Cohort in Kisumu, Kenya.

Elisavet Serti, Danielle Bartolanzo, Seth Frndak, John Owuoth, Adam Yates, Tyler Hamby, Chiaka Nwoga, June Otieno, Hunter J Smith, Glenna Schluck and 4 more

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In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elisavet SertiU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.ORCID 0000-0003-4129-0254
Danielle BartolanzoU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
Seth FrndakU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
John OwuothHJF Medical Research International, Kisumu, Kenya.
Adam YatesU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
Tyler HambyU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
Chiaka NwogaU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
June OtienoHJF Medical Research International, Kisumu, Kenya.
Hunter J SmithGlobal Emerging Infections Surveillance Branch, Armed Forces Health Surveillance Division, Silver Spring, MD.
Glenna SchluckU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
Christina S PolyakU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
Valentine Sing'oeiHJF Medical Research International, Kisumu, Kenya.
Trevor A CrowellU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD.
RV393 Study team

Funding

U.S. Department of Defense HT94252430004U.S. Department of Defense W81XWH-11-2-0174U.S. Department of Defense W81XWH-18-2-0040
6 · The paper itself

Abstract

backgroundAdherence to study visits enhances safety and validity of human research studies. We identified characteristics associated with missed visits in a Kenyan HIV incidence study to inform retention strategies.

methodsWe enrolled volunteers 18-35 years of age, without HIV, who reported 2+ sex partners into a study with visits every 3 months for 24 months. We used zero-inflated Poisson regression to assess sociobehavioral and demographic characteristics associated with missed visits and loss-to-follow-up. Latent class analysis (LCA) identified clusters of characteristics associated with each outcome.

resultsAmong 619 participants without HIV, 278 (44.9%) were women with median age of 24 years (interquartile range: 21-28). During follow-up, 134 (21.6%) missed 1+ and 84 (13.6%) missed 2+ visits. Missed visits were more common among participants with 3+ sexual partners than among 2 partners (adjusted risk ratio: 1.50, 95% confidence interval: 1.13 to 1.97) and less common in participants who completed secondary school (aRR: 0.74, 95% CI: 0.56 to 0.99, compared with some primary school or less). Women were more likely to be lost to follow-up (aRR: 1.85, 95% CI: 1.05 to 3.26). LCA showed that missed visits were more likely among women aged 24+ years with less than secondary education who reported transactional sex than among largely younger unmarried men with less than secondary education and 3+ sexual partners (RR: 1.24, 95% CI: 1.01 to 1.54) and poorly educated, largely older married men (RR: 1.41, 95% CI: 1.05 to 1.90).

conclusionOlder unmarried women with less education, more sexual partners, and transactional sex may benefit from targeted retention strategies such as optimizing accessibility to testing and prevention services and frequent visit reminders.

Indexed as

HIV InfectionsLost to Follow-UpPatient ComplianceAdolescentAdultCohort StudiesFemaleHumansIncidenceKenyaMaleSexual PartnersYoung Adultcohort studiesHIVKenyalost to follow-upnonadherenceprotocol compliance

Identifiers

PMID41452204
PMCPMC13588939

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.