Evidence map›Paper›PMID 41451998›Full record

ArticlePhysiological reports2025

Breakfast skipping and steroid withdrawal in ulcerative colitis: A population-based study in Japan.

Hiroshi Fukuda, Haru Miyagi, Kenta Yamamoto

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hiroshi FukudaFaculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, Japan.
Haru MiyagiFaculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, Japan.
Kenta YamamotoFaculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, Japan.ORCID 0009-0009-5236-5160

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) JP2011422SMEXT | Japan Society for the Promotion of Science (JSPS) JP20K11422MEXT | Japan Society for the Promotion of Science (JSPS) JP23K10722
6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with increasing prevalence in Japan. While pharmacological therapies have advanced, the effect of dietary timing, particularly breakfast skipping, on disease course remains unclear. We conducted a retrospective cohort study using the JMDC database (2015-2023), which contains claims and annual health checkup data from about 8.17 million insured individuals. We identified 1645 UC patients who initiated corticosteroid therapy within 1 year after diagnosis and were followed for at least 3 years. Breakfast skipping was defined as skipping breakfast more than three times per week. The primary outcome was steroid withdrawal, defined as discontinuation of corticosteroid prescriptions. Logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) for steroid withdrawal according to breakfast habits. Among 1645 patients, 303 (18.4%) reported skipping breakfast. Steroid withdrawal occurred in 543 patients (33.0%), including 108 (35.6%) in the breakfast skipping group and 435 (32.4%) in the breakfast consuming group. In fully adjusted models accounting for 5-aminosalicylic acid and immunosuppressant use, breakfast skipping was associated with higher odds of steroid withdrawal (OR 1.52, 95% CI 1.08-2.14). These findings suggest that meal timing may influence sustained remission in UC.

Indexed as

Adrenal Cortex HormonesBreakfastColitis, UlcerativeFeeding BehaviorAdultAgedFemaleHumansIntermittent FastingJapanMaleMiddle AgedRetrospective StudiesAdrenal Cortex Hormonesbreakfast skippinghealth checkupintermittent fastingsteroid withdrawalulcerative colitis

Identifiers

PMID41451998
PMCPMC12742014

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.