Evidence map›Paper›PMID 41451990›Full record

ArticleMicrobiology spectrum2026

Epidemiology of healthcare-associated ventriculitis and meningitis (HCAVM) and community-acquired meningitis/encephalitis and evaluation of an off-label PCR panel for HCAVM diagnosis.

Jamie A Nassur, Katarina M Schnell, Christine D Dolon, Laura Walters, Devin Weber, Matthew A Pettengill

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jamie A NassurThomas Jefferson University, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.
Katarina M SchnellDepartment of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Christine D DolonDepartment of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Laura WaltersThomas Jefferson University, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.
Devin WeberThomas Jefferson University, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.
Matthew A PettengillThomas Jefferson University, Sidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4579-0187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare-associated ventriculitis and meningitis (HCAVM) is associated with high morbidity and mortality, but rapid diagnostic tests intended to cover microorganisms that typically cause HCAVM are not commercially available. We sought to evaluate the etiology of HCAVM compared to community-acquired meningitis/encephalitis (CAME) at our healthcare system, and to study the utility of repurposing a multiplex molecular panel intended for positive blood cultures for HCAVM cases. Our epidemiologic review demonstrated that HCAVM cases were primarily caused by bacteria and fungi also associated with bloodstream infections, in contrast with CAME cases, which were primarily caused by herpesviruses and

Indexed as

Cerebral VentriculitisCommunity-Acquired InfectionsCross InfectionEncephalitisMeningitisPolymerase Chain ReactionAdolescentAdultAgedBacteriaChildChild, PreschoolFemaleHumansMaleMiddle AgedmeningitisnosocomialPCRrapidventriculitis

Identifiers

PMID41451990
PMCPMC12889075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.