ArticlePublic health nutrition2025
Nutritional deficiencies among adults with beta thalassemia major in Vietnam.
Article in Public health nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- A Scoring System for the Assessment of Quality of Care in the Management of Transfusion Dependent Thalassemia.Hematology reports · 2026Review
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7 authors.
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Abstract
objectiveTo evaluate the nutritional status of adults with beta thalassemia major in Vietnam by analysing body composition parameters and assessing the adequacy of energy, macronutrient and micronutrient intake.
designA cross-sectional study was conducted among adult patients with beta thalassemia major. Nutritional status was assessed using three components: BMI, body composition and dietary intake.
settingDepartment of Thalassemia, The National Institute of Hematology and Blood Transfusion in Vietnam.
participants317 adult patients with beta thalassemia major (54·2 % females, median age 32).
resultsNearly half (49·5 %) of the patients had a normal BMI, while 18·3 % were severely underweight and 32·2 % were underweight. Severe underweight patients exhibited lower body fat, bone mineral content and visceral fat. Average daily energy intake (1449·9 kcal) was significantly below the estimated requirement (2079·5 kcal), with 81·4 % of patients consuming less than 85 % of their energy needs. Severely underweight patients consumed 12·06 g/d less fat (95 % CI: 6·85, 17·26) and 10·42 g/d less protein (95 % CI: 4·42, 16·42) than normal weight patients. Severe deficiencies in Ca, Mg, Fe and B-complex vitamins were prevalent, with the lowest mean probability of adequacy for minerals and vitamins observed in severely underweight patients.
conclusionThis study provides the first comprehensive assessment of the nutritional status of beta thalassemia major patients in Vietnam, revealing critical gaps in energy and nutrient intake. Evidence-based strategies, including dietary education and interventions tailored to the unique needs of this population, are urgently needed to improve nutritional outcomes and overall health.
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