ArticleNature electronics2025
A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice.
Article in Nature electronics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Low-power analog and mixed-signal circuit techniques for next-generation miniature implantable neural interface systems.Biomedical engineering letters · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Funding
Abstract
The long-term recording of neural activity could be used to understand complex behaviours and disorders. However, the development of technology capable of such measurements faces a variety of technical challenges, including the relative motion between recording electrodes and tissue and the excessive displaced volume from implanted electronics. Here we report a subnanolitre-volume tetherless optoelectronic microsystem for neural recording. The system relies on light for photovoltaic power and data transfer, through a light-emitting diode, eliminating the need for wires or other tethers. It uses a single AlGaAs diode as both photovoltaic and light-emitting diode. Complementary metal-oxide-semiconductor circuits provide low-noise amplification, pulse-position-modulated encoding and electro-optical transduction. Two-dimensional materials processing techniques, vacuum annealing and atomic layer deposition, in conjunction with a standard complementary metal-oxide-semiconductor fabrication process, provide compact encapsulation against the corrosive conditions of biological media. We show that the subnanolitre neural implant is capable of chronic (365 days) in vivo recordings in awake mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.