Evidence map›Paper›PMID 41451215›Full record

ReviewFrontiers in immunology2025

Research progress on the role and mechanism of circadian clock gene

Yuxiang Zhao, Yujin Li, Tingting Lu, Xinyue Huang, Kerui Chen, Lina Tan, Lihua Gao

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuxiang ZhaoDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yujin LiDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Tingting LuDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xinyue HuangDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Kerui ChenDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Lina TanDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Lihua GaoDepartments of Dermatology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian rhythm, an inherent 24-hour periodic rhythm in organisms, is regulated by circadian clock genes. As a key component of the transcription-translation feedback loop, the core circadian gene period (

Indexed as

Circadian ClocksPeriod Circadian ProteinsAnimalsCardiovascular DiseasesCircadian RhythmHumansMetabolic DiseasesNeoplasmsNervous System DiseasesPER1 protein, humanPeriod Circadian Proteinscardiovascular diseasescircadian rhythmimmune system diseasesmetabolic disordersnervous system diseasesperiod 1tumors

Identifiers

PMID41451215
PMCPMC12727441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.