ReviewAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2025
Evidence-Based Recommendations for Geriatric Trauma Care: Systematic Review and AI-Assisted Consolidation of Clinical Practice Guidelines Between 2016 and 2021.
Review in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This systematic review provides a comprehensive overview of evidence-based clinical practice guidelines (CPGs) for geriatric trauma care through the utilization of a novel artificial intelligence (AI) methodology. Background: With a growing proportion of trauma cases involving geriatric patients, there is a need for tailored management considering their unique challenges related to multimorbidity and frailty. Evidence-based recommendations support clinical decision-making in this population. Methods: MEDLINE Ovid and 8 guideline databases were searched on December 18, 2021, for CPGs published after January 1, 2016. Eligible CPGs were required to be published in German or English, have an evidence assessment (such as Grading of Recommendations, Assessment, Development and Evaluation (GRADE)), report at least 1 recommendation for older patients (≥60 years, frail, or with dementia/delirium) applicable in an acute inpatient trauma setting, and achieve an Appraisal of Guidelines for Research & Evaluation II (AGREE II) overall quality rating of at least 4 points rated by 2 independent experts. The extracted CPG recommendations underwent semantic analysis with AI-based natural language processing, followed by dimensional reduction and grouping via Results: After screening, full-text review, and AGREE II appraisal, 95 CPGs out of 12,106 records were included, yielding 821 CPG recommendations relevant to geriatric trauma care. Most recommendations addressed dementia, delirium, adverse drug reactions, deprescribing, multimorbidity, frailty, and cardiovascular disease. The clustering analysis identified 27 clusters of semantically similar recommendations, and each cluster was consolidated into a single meta-recommendation. Conclusions: Our systematic review provides a comprehensive summary of evidence-based CPG recommendations for geriatric trauma care, offering clinicians a solid foundation for managing this vulnerable patient population.
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