ArticleFrontiers in medicine2025
Preliminary study on the influencing factors of Young's modulus of viscoelastic model detected by shear wave elasticity.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim: The objective of this study is to investigate the influence of various components, viscosity, ultrasonic frequency, and depth of the region of interest on Young's modulus of the viscoelastic model. Methods: Viscoelastic models, characterized by distinct viscosities and compositions, were fabricated using gelatin as the elastomeric component, fructose as the viscous component, and milk powder as an additive ingredient. Shear wave elastography (SWE) technology was utilized, with the acoustic frequencies set at 7 MHz, 8 MHz, and 9 MHz, respectively. Additionally, the depths of regions of interest (ROI) were varied at 1 cm, 2 cm, and 3 cm to enable a comparison of Young's modulus values across different viscoelastic body models. Results: In order to generate viscoelastic models with varying compositions, gelatin samples with the same concentration were prepared with different concentrations of fructose added. Under consistent frequency and ROI depth conditions, no statistically significant differences were observed in the measured Young's modulus values among these models ( Conclusion: The self-constructed viscoelastic model demonstrates convenience and adaptability, allowing flexible control over its viscosity and composition. Under varying conditions, the factors determining Young's modulus differ; elements such as compositional heterogeneity, frequencies, and ROI depth all influence the modulus.
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