Evidence map›Paper›PMID 41451102›Full record

ArticleFrontiers in medicine2025

Therapeutic keratopigmentation Vis-à-Vis in blind eyes: complications and outcomes in a series of 184 eyes.

Alexandre Xavier da Costa, André França Fontes Cal, Munik Pereira Bannach, Gizeli Horta de Oliveira, Giovanni Garotti

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandre Xavier da CostaDepartment of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
André França Fontes CalHospital de Olhos Hilton Rocha, Belo Horizonte, Brazil.
Munik Pereira BannachHospital Santo Amaro, São Paulo, Brazil.
Gizeli Horta de OliveiraIPSEMG - Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte, Brazil.
Giovanni GarottiDepartment of Ophthalmology, Universidade de Sao Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the outcomes, complications, and patient satisfaction following therapeutic keratopigmentation Vis-à-Vis in blind eyes. Methods: This retrospective case series included 184 eyes from blind patients who underwent KTP between 2016 and 2024, using either inorganic or mixed pigments. Superficial automated, superficial manual, and intrastromal manual approaches were performed according to corneal indication. Data collected comprised demographic information, surgical techniques, pigment type, postoperative complications, re-epithelialization time, and long-term stability. Patient-reported outcomes regarding cosmetic satisfaction and quality-of-life impact were also assessed. Results: The overall median re-epithelialization time was 14 days, though delayed healing occurred in < 20% of the patients. Postoperative complications included pigment fading, infectious keratitis, photophobia and corneal melting, though most were manageable and did not compromise final cosmetic outcomes. Cases of MRI-related ocular discomfort were noted in eyes pigmented with iron oxide-based compounds but resolved without structural alterations. At final follow-up, cosmetic appearance was graded as good to excellent in 90% of cases, and 88% of patients expressed high satisfaction, reporting improved psychosocial wellbeing. Conclusion: Therapeutic keratopigmentation Vis-à-Vis emerges as a meaningful intervention for blind eyes, not merely restoring external harmony but also restoring dignity and quality of life. Even with a tangible risk of complications, long-term pigment stability and high satisfaction rates highlight its value as both a reconstructive and humanizing procedure in corneal surgery.

Indexed as

blind eyecorneal opacitiescorneal tattooingcosmetic outcomeskeratopigmentationkeratopigmentation Vis-à-Visocular surface surgerytherapeutic keratopigmentation

Identifiers

PMID41451102
PMCPMC12727935

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.