Evidence map›Paper›PMID 41451038›Full record

ArticleGeneral psychiatry2025

Global burden of mental disorders among adolescents and young adults, 1990-2021: a systematic analysis of the Global Burden of Diseases Study 2021.

Jiayi Tian, Na Yan, Xinyi Hu, Susu Tian, Yuhao Wang, Louisa Esi Mackay, Yunjiao Luo, Yingxue Wang, Yihan Wang, Yuxuan Liu and 8 more

Abstract read
In one paragraph

Article in General psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jiayi TianSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Na YanSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Xinyi HuSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Susu TianSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yuhao WangSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Louisa Esi MackaySchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yunjiao LuoSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yingxue WangSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yihan WangSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Yuxuan LiuSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Blen Dereje ShiferawSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Huihang LanDepartment of General Practice, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Wenjun YanSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Qingzhi WangSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Xiuyin GaoSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Caiyi ZhangDepartment of Psychiatry, The Affiliated Xuzhou Oriental Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Haibo XuSchool of Management, Xuzhou Medical University, Xuzhou, Jiangsu, China.ORCID https://orcid.org/0000-0003-2139-999X
Wei WangSchool of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, China.ORCID https://orcid.org/0000-0003-3746-7280

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mental disorders pose a significant global health burden, especially after the coronavirus disease 2019 pandemic. Aims: This study aimed to characterise trends in the burden of mental disorders among adolescents and young adults by sex, age, sociodemographic index (SDI) quintile, region and country from 1990 to 2021. Methods: Estimates and 95% uncertainty intervals (UIs) for disability-adjusted life years (DALYs) were extracted from the Global Burden of Diseases Study 2021. The number and rate of DALYs, as well as the percentage change from 1990 to 2021, were estimated by sex, age, SDI quintile, region and country. Results: The number of DALYs for mental disorders increased from 26.1 (95% UI 19.3 to 34.4) million to 36.3 (26.6 to 48.1) million. The DALY rate increased from 1687.8 (1245.3 to 2225.4) per 100 000 population in 1990 to 1923.7 (1408.7 to 2548.4) per 100 000 population in 2021, representing a 14% (12% to 16%) increase. Females (16% (13% to 18%)) and individuals aged 15-19 years (16% (13% to 18%)) showed the greatest increase in DALY rates. Between 1990 and 2021, DALY rates rose significantly across all SDI quintiles and regions, except East Asia (-5% (-9% to -1%)). The most rapid increases were observed in parts of Latin America, particularly for anxiety and depressive disorders. Conclusions: The global burden of mental disorders among adolescents increased significantly from 1990 to 2021, necessitating attention to policies targeting high-risk populations and specific regions.

Indexed as

Adolescent PsychiatryAnxietyAutism Spectrum DisorderDepressive DisorderMental Disorders

Identifiers

PMID41451038
PMCPMC12730781

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.