ArticleInternational journal of extreme manufacturing2026
Hyaluronic Acid-Based Bioink for Anisotropic Neural Tissue Cryobioprinting.
Article in International journal of extreme manufacturing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Biomimetic scaffolds based on stem cells for neural tissue engineering: a review.Stem cell research & therapy · 2026Review
- A mechanobiology-driven cell-derived ECM bioink for engineering 3D glioblastoma tumor microenvironment models.Theranostics · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
In this study, we present the development of a cryobioink designed to fabricate anisotropic scaffolds that support both neural and muscle cell alignment. Given the critical role of cellular organization in nerve fibers and neuromuscular junctions, we employed a vertical cryobioprinting-enabled ice-templating technique to create scaffolds with aligned microchannels. These channels facilitated cell alignment, which is important in modeling neural and neuromuscular tissues. By integrating hyaluronic acid-methacrylate (HAMA) with gelatin methacryloyl and the necessary cryoprotective agent melezitose, we showcased that the cryobioink could preserve cell viability during freezing/thawing processes, even at low temperatures employed during cryobioprinting. We optimized HAMA concentration to enhance neural cell viability and alignment, and successfully constructed anisotropic scaffolds featuring distinct sections that contained muscle and neural cells, establishing a model for neuromuscular junctions. The resulting models provide a versatile platform for studying nerve fibers and neuromuscular dysfunctions, offering potential advancements in neural regeneration research.
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Registered trials
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