Evidence map›Paper›PMID 41450870›Full record

ArticleBrain & spine2025

Location-specific outcomes and complications of endoscopic transorbital approaches: A systematic review with novel anatomical grouping.

Sophia C Lam, Jason Y S Cheung, Ben C F Ng, Hunter K L Yuen, Calvin H K Mak

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sophia C LamDepartment of Neurosurgery, Queen Elizabeth Hospital, Hong Kong, China.
Jason Y S CheungFaculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Ben C F NgDepartment of Neurosurgery, Queen Elizabeth Hospital, Hong Kong, China.
Hunter K L YuenDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Calvin H K MakDepartment of Neurosurgery, Queen Elizabeth Hospital, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Endoscopic transorbital approach (ETOA) is gaining recognition due to lower complication rates and better cosmetic outcomes. Nonetheless, there is no clear anatomical grouping system for lesions that ETOA can address, and location-specific complication rates are still lacking. Research question: This systematic review provides an anatomical grouping system for ETOA and analyse the location-specific surgical risks and outcomes. Material and methods: Based on the PRISMA guideline, articles with keywords "Endoscopic" and "Transorbital" were searched and analysed. The cases included are regrouped based on four anatomical locations (I - orbital, II - cavernous sinus, III - extradural, IV - intradural), and outcomes are studied respectively. Results: Data from 28 published articles with 382 patients were identified. There were 113 orbital lesions, 58 cavernous lesions, 18 extradural lesions, and 150 intradural lesions. There was significant post-operative visual acuity improvement in Groups I (70.6 %), II (56.3 %), and IV (63.3 %). Proptosis shows notable improvement rates across all groups, particularly in Groups II (95.7 %) and IV (87.0 %). There was an observed difference in the rate of CSF leak depending on the location of the lesion: 0 % in both Group I and II versus 11.8 % in Group III and 3.4 % in Group IV ( Discussion and conclusion: This systematic review proposed an anatomical grouping system to analyse location-specific outcomes for ETOA. Our findings highlighted the significance of this new classification for anatomy-based risk assessment. Future, larger-scale, and multicenter research will generate more data, allowing for further stratification of outcomes based on specific pathology subtypes.

Indexed as

Endoscopic surgeryETOATransorbital approach

Identifiers

PMID41450870
PMCPMC12731732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.