Evidence map›Paper›PMID 41450850›Full record

ReviewInterventional cardiology (London, England)2025

Breaking the Barriers: Transseptal Puncture in Patients with Atrial Septal Defect Closure Devices.

Gerardo Lo Russo, Roberto Nerla, Angela Sanseviero, Gianluca Pillitteri, Mattia Cubich, Paolo Sbarzaglia, Marco Toselli, Fausto Castriota

Abstract readReview
In one paragraph

Review in Interventional cardiology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gerardo Lo RussoGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.ORCID https://orcid.org/0000-0001-6701-0308
Roberto NerlaGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.ORCID https://orcid.org/0000-0002-9065-3261
Angela SansevieroGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.
Gianluca PillitteriGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.ORCID https://orcid.org/0009-0001-5430-0194
Mattia CubichGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.
Paolo SbarzagliaGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.
Marco ToselliGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.ORCID https://orcid.org/0000-0003-4055-5062
Fausto CastriotaGVM Care & Research, Maria Cecilia Hospital Cotignola, Italy.ORCID https://orcid.org/0000-0001-5936-9863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial septal defect and patent foramen ovale are common congenital heart defects in adults, often treated with atrial septal occluders (ASOs) via percutaneous closure. Transseptal puncture (TSP) for left atrial interventions in patients with ASOs presents procedural challenges, requiring detailed pre-procedural planning and imaging. Transoesophageal echocardiography and cardiac CT help identify optimal puncture sites, either through the native septum or across the ASO. Advanced techniques, such as balloon-assisted tracking and radiofrequency energy delivery, aid in navigating the device. TSP is frequently performed for procedures such as pulmonary vein isolation, left atrial appendage occlusion, and mitral valve interventions. While generally safe and effective, TSP can lead to complications including residual shunting and device deformation, or procedural delays. Specialised expertise and multimodality imaging are crucial for optimising success and minimising risks. This review outlines TSP techniques, clinical applications and strategies for navigating ASOs during left atrial interventions.

Indexed as

Atrial septal occluder deviceleft atrial appendage occlusionmitral valve interventionpulmonary vein isolationtransseptal puncturetransseptal puncture by device

Identifiers

PMID41450850
PMCPMC12728519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.