ArticleJournal of Indian Society of Periodontology
Porous Ti6Al4V with controlled oxidation toward improved osseointegration of dental implant.
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Titanium (Ti) implants are known to be bioinert, stress shielding, and poor osseointegration, due to modulus discrepancy with native bone. This research aims to design a porous Ti6Al4V implant with controllable oxidation to mimic the natural bone properties for better osseointegration. Materials and Methods: Porous Ti6Al4V foams were manufactured by coagulant-assisted metal foaming with egg white protein and citric acid as stabilizing matrix. The detailed characterization was conducted using X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, nanoindentation, and microcomputed tomography (micro-CT) to characterize microstructural, porosity, and mechanical properties. MTT assay and dual staining were used to study Results: The fabricated porous Ti6Al4V implants had 71%-75% porosity, facilitating nutrient transport and cellular ingrowth. Compressive modulus (284 MPa), measured via mechanical testing, was comparable to that of trabecular bone. Conclusions: Controlled oxidation of porous Ti6Al4V foam could provide a potential way to overcome the current limitations of dental implants. The improved biomechanical compatibility and osseointegration support its potential for clinical application in implantology.
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