Evidence map›Paper›PMID 41450798›Full record

ArticleJournal of Indian Society of Periodontology

Efficacy of hyaluronic acid on the inhibition of periodontal bridging organisms

Sanjeevini Hattarki, Sandeep S Katti, K V Madhushree, Vaishali Rathod, Shivani Kadam, Anisha Jose

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sanjeevini HattarkiDepartment of Periodontology, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, Karnataka, India.
Sandeep S KattiDepartment of Periodontology, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, Karnataka, India.
K V MadhushreeDepartment of Periodontology, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, Karnataka, India.
Vaishali RathodDepartment of Periodontology, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, Karnataka, India.
Shivani KadamDepartment of Periodontology, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, Karnataka, India.
Anisha JoseDepartment of Periodontology, Annoor Dental College and Hospital, Ernakulam, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This Materials and Methods: Standard laboratory strains of Results: HA showed concentration-dependent bacteriostatic effects. Conclusion: High-molecular-weight HA shows potential as a nonantibiotic support agent in periodontal therapy by selectively inhibiting key anaerobic bacteria involved in biofilm development. Its two actions, antimicrobial and immunomodulatory, highlight its importance by breaking down pathogenic cooperation and supporting periodontal healing. Further research with multispecies biofilms, clinical isolates, and host interaction models is necessary for clinical application.

Indexed as

Fusobacterium nucleatumhyaluronic acidminimum inhibitory concentrationperiodontal pathogensperiodontitisPrevotella intermedia

Identifiers

PMID41450798
PMCPMC12736737

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.