ReviewFrontiers in toxicology2025
Enhancing allergenicity risk assessment for novel foods in the EU: insights from the updated EFSA guidance - requirements, knowledge gaps and research needs.
Review in Frontiers in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Chia Seed Allergy: Emerging Clinical Evidence, Molecular Allergens, and the Unresolved Question of Cross-Reactivity.Nutrients · 2026Review
- Allergenicity Assessment of Precision Fermentation-Derived Food Proteins.Foods (Basel, Switzerland) · 2026Review
- Review
- Prediction of plant food allergens using protein embeddings.Bioinformatics advances · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With growing interest in new protein sources, driven by market trends and European Union (EU) food policy priorities, novel proteins are entering the market. These novel foods (NFs) might have the potential of introducing new allergens into the diet. In the EU, the European Food Safety Authority (EFSA) is tasked with assessing the safety of NFs and has recently updated its scientific guidance to reflect advancements in food science and built-up experience in NF risk assessment (RA). EFSA's allergenicity RA strategy follows a weight-of-evidence approach. Data requirements depend on whether the NF is produced from or with materials containing protein, derived from known allergenic foods (whether subject to mandatory labelling or not), or has unknown allergenic potential. For the latter, a tiered approach focused on assessing the cross-allergenicity potential is applied to single proteins, protein mixtures and whole foods. However, allergenicity RA continues to face challenges including the availability of reference standard materials and the lack of agreement on the interpretation of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.