Evidence map›Paper›PMID 41450687›Full record

ArticleFrontiers in psychology2025

AI-driven music intervention based on five-tone theory for anxiety: a preliminary pre-post feasibility study.

Xu Rongrong, Li Jing

Abstract read
In one paragraph

Article in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xu RongrongSchool of Music and Dance, Xuchang University, Xuchang, China.
Li JingSchool of Arts, Zhejiang Normal University, Jinhua, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Music therapy, as a pivotal non-pharmacological intervention, faces a critical challenge in designing personalized treatment protocols. Current clinical applications of the traditional Chinese five-tone theory to explore the relationship between music and emotion lack empirical validation and scalable implementation. This study integrates the five-tone theory with artificial intelligence (AI) to develop an AI-driven music modulation system based on real-time physiological feedback, aiming to examine its efficacy in alleviating anxiety symptoms and modulating the autonomic nervous system. A single-group pretest-posttest design was employed, with 40 university students exhibiting moderate anxiety (M_age = 21.5) enrolled as participants. Each underwent a 20-min intervention session. The system employed the Jue tone as the foundational pitch, with real-time dynamic modulation guided by heart rate variability (HRV) and electrodermal activity (EDA) data. The Hamilton Anxiety Rating Scale (HAMA), high-frequency HRV (HF-HRV), and skin conductance level (SCL) were employed in pre-post measurements. Post-intervention statistical analyses revealed a statistically significant reduction in HAMA scores (M_pre = 18.2 vs. M_post = 11.5,

Indexed as

anxietyartificial intelligenceautonomic nervous systembiofeedbackfive-tone theoryheart rate variabilitymusic therapy

Identifiers

PMID41450687
PMCPMC12728001

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.