ArticleJACS Au2025
Self-Reporting Aggregation-Induced Emission Gene Transfection System via Multivalent Tetrazole-Amine Complexation.
Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Nondestructive tracking of viral infections by viral protein-initiated fluorescent sensors.Journal of virology · 2026Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Gene transfection visualization provides intuitive and direct evidence of gene function and cellular signaling pathways through dynamic, real-time tracking of gene delivery and expression. In this work, we synthesized two tetraphenylethylene-backboned AIE (aggregation-induced emission) fluorophores with acidic tetrazole moieties, which were subsequently integrated with branched polyethylenimine (BPEI) gene carriers via electrostatic interactions to construct a fluorescent gene delivery complex system. This self-reporting gene delivery platform combines responsive AIE fluorescence properties with good biocompatibility while maintaining the vector's binding competence to the host cell in living systems. By employing GFP (green fluorescence protein)-tagged plasmid DNA in a proof-of-concept study, the system enables real-time spatiotemporal tracking and precise localization of gene transporting processes into HeLa cells. Quantitative flow cytometric analysis revealed enhanced transfection efficiency for the
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