Evidence map›Paper›PMID 41450571›Full record

ArticleFrontiers in cellular and infection microbiology2025

Overexpression of the major facilitator superfamily efflux pump gene

Chenchen Si, Qiang Jiang, Poshi Xu, Tao Li, Shixuan Hua, Zhenjun Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chenchen SiDepartment of Medical Laboratory, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Qiang JiangDepartment of Oncology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Poshi XuDepartment of Medical Laboratory, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Tao LiDepartment of Medical Laboratory, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Shixuan HuaDepartment of Medical Laboratory, Fuwai Central China Cardiovascular Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Zhenjun LiNational Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To explore the molecular basis of ciprofloxacin resistance in Methods: We analyzed 20 Results: Sequencing revealed no resistance-associated mutations in Conclusion: This study identifies the overexpression of specific MFS efflux pump genes, particularly

Indexed as

Anti-Bacterial AgentsBacterial ProteinsCiprofloxacinDrug Resistance, BacterialMembrane Transport ProteinsNocardiaDNA GyraseGene Expression Regulation, BacterialHumansMicrobial Sensitivity TestsPorinsAnti-Bacterial AgentsBacterial ProteinsCiprofloxacinDNA GyraseMembrane Transport ProteinsPorinsciprofloxacinefflux pumpefflux pump inhibitorsmajor facilitator superfamilyNocardia farcinicaporin generesistance mechanisms

Identifiers

PMID41450571
PMCPMC12727967

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.