ArticleReproductive medicine and biology
Risk of Placenta Accreta Spectrum With Early Pregnancy Subchorionic Hematoma Location and Size in Hormone Replacement Cycles.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Hormone Replacement Cycle Frozen-Thawed Embryo Transfer Is Associated With Elevated Perinatal Risk Compared With Natural Ovulatory Cycle Frozen-Thawed and Fresh Embryo Transfers: Retrospective Analysis of 7,593 Live Birth Cycles.Reproductive medicine and biologyArticle
- Risk of Placenta Accreta Spectrum With Early Pregnancy Subchorionic Hematoma Location and Size in Hormone Replacement Cycles.Reproductive medicine and biologyArticle
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Purpose: To study whether subchorionic hematoma (SCH) location and size in early pregnancy affect placenta accreta spectrum (PAS) risk in hormone replacement cycles (HRC). Methods: Retrospective cohort study of 685 singleton live births following frozen-thawed embryo transfer in HRC (November 2018-September 2023) at a single fertility clinic. SCH location (cervical-side, mid-cavity, or fundal-side) and size (< 10% or > 50% of gestational sac), assessed by first-trimester ultrasound, were evaluated for association with PAS. Results: The presence of SCH showed a trend toward increased PAS frequency (adjusted Risk Ratio (RR) 1.56, 95% Confidence Interval (CI) 0.87-2.80). Location-specific analysis revealed that cervical-side SCH conferred significantly elevated PAS risk compared to those without cervical-side SCH (adjusted RR 2.21, 95% CI 1.18-4.15), whereas mid-cavity SCH (adjusted RR 1.74, 95% CI 0.94-3.22) and fundal-side SCH (adjusted RR 0.59, 95% CI 0.20-1.76) showed no significant association. Regarding SCH size, larger hematomas (> 50% of gestational sac) were not associated with increased PAS risk compared to smaller hematomas (< 10%) (adjusted RR 0.59, 95% CI 0.16-2.13). Conclusions: Cervical-side SCH, but not mid-cavity or fundal-side hematomas, was associated with increased PAS risk in HRC pregnancies. These findings suggest that SCH location may serve as a key prognostic marker in HRC.
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