ArticleFrontiers in aging neuroscience2025
Prognostic value of endothelial activation and stress index in mechanical thrombectomy for patients with acute ischemic stroke.
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
Background and purpose: The Endothelial Activation and Stress Index (EASIX) is a marker of endothelial dysfunction. This study aimed to explore the association between the EASIX score and unfavorable outcome in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy (MT) treatment. Methods: We enrolled AIS patients treated with MT from a multicenter study between June 2021 to September 2024. The EASIX score was calculated as lactate dehydrogenase (LDH) (U / L) × Creatinine (mg / dL) / Platelet Count (10 Results: A total of 406 patients (258 [63.5%] male and median age: 71 years) were included in this study. 181 (44.6%) patients experienced unfavorable outcome. The logistic regression models demonstrated a robust association between the EASIX score and unfavorable outcome (log2 transformed odds ratio [OR]: 1.41; 95% confidence interval [CI]: 1.19-1.70; Conclusion: Higher EASIX levels were significantly related to unfavorable outcome in AIS patients treated with MT. EASIX score may serve as a valuable tool for early risk assessment and outcome prediction in AIS patients.
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