Evidence map›Paper›PMID 41450524›Full record

ArticleFrontiers in public health2025

Low education and employment status drive cardiometabolic health: a social determinants perspective in Chinese population.

Jia-Feng Zhang, Xin-Yi Cai, Wei Tang, Yan Song, Xing-Xing Zhang, Yong-Quan Shi, Tuo Li

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia-Feng Zhang *Department of Laboratory Medicine, Changzheng Hospital, Shanghai, China.
Xin-Yi Cai *Department of Endocrinology, Changzheng Hospital, Shanghai, China.
Wei TangDepartment of Endocrinology, Changzheng Hospital, Shanghai, China.
Yan SongDepartment of Endocrinology, Changzheng Hospital, Shanghai, China.
Xing-Xing ZhangDepartment of Endocrinology, Changzheng Hospital, Shanghai, China.
Yong-Quan ShiDepartment of Endocrinology, Changzheng Hospital, Shanghai, China.
Tuo LiDepartment of Endocrinology, Changzheng Hospital, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular-kidney-metabolic (CKM) syndrome has emerged a major strain on healthcare systems worldwide, with marked disparities in incidence across different regions, which are partly attributed to social determinants of health (SDOH). While research has touched upon the link between SDOH and CKM, and isolated SDOH factor's influence on cardiovascular health has been probed in China, evaluation of how SDOH collectively affect CKM in Chinese population remains underexplored in a systematic fashion. Methods: The study drew on Shanghai community population (STONE cohort, Results: Unfavorable SDOH profiles, including limited schooling (OR = 8.18; 95% CI: 6.16-10.86), unemployment or retirement (OR = 11.38; 95% CI: 8.59-15.08), and low income (OR = 2.24; 95% CI: 1.78-2.81) were robustly linked to CKM advancement independent of classic metabolic risk factors. The effect was present only among adults aged 36-50 years (OR = 2.45; 95% CI: 1.37-4.40). Women clear of alcohol displayed elevated odds with advanced CKM stages, whereas men did not show significant association with CKM progression. Conclusion: Unfavorable SDOH, especially low education and unemployed or retired, and limited income, constitute independent determinants of CKM progression. Embedding SDOH metrics into routine CKM surveillance and designing targeted interventions for mid-life adults and women could transform primary prevention strategies.

Indexed as

Cardiovascular DiseasesEducational StatusEmploymentMetabolic SyndromeSocial Determinants of HealthAdultAgedChinaEast Asian PeopleFemaleHumansMaleMiddle AgedRisk Factorscardiovascular-kidney-metabolic (CKM) syndromeeducationemploymentincomesocial determinants of health (SDOH)

Identifiers

PMID41450524
PMCPMC12727962

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.