Evidence map›Paper›PMID 41450489›Full record

ArticleFrontiers in public health2025

Prevalence and associations of adverse childhood experiences with anxiety and depressive symptoms in Indonesia.

Karen Arulsamy, Elmeida Effendy, Sarah Mardhiyah, Mustafa M Amin, M Surya Husada, Vita Camellia, Anne-Claire Stona, Eric Andrew Finkelstein

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Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Karen ArulsamyLien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.
Elmeida EffendyDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Sarah MardhiyahDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Mustafa M AminDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
M Surya HusadaDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Vita CamelliaDepartment of Psychiatry, Universitas Sumatera Utara, Medan, Indonesia.
Anne-Claire StonaSingHealth-Duke Global Health Institute, Duke-NUS Medical School, Singapore, Singapore.
Eric Andrew FinkelsteinLien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Research in Southeast Asia-particularly Indonesia-on the link between adverse childhood experiences and adult mental health remains limited. The current study aims to examine the prevalence of ACEs in Indonesia, associations with anxiety and depressive symptoms among adults, and gender differences. Methods: We conducted an online cross-sectional survey of 872 Indonesians aged 21-64 years. ACEs were measured using the WHO ACE-IQ, and anxiety and depressive symptoms with the PHQ-2, GAD-2, and their composite PHQ-4. Associations between ACEs and symptoms were analyzed using weighted regression models adjusting for demographic variables. Results: ACEs were highly prevalent (79.5%), most commonly parental separation (50.9%), emotional neglect (39.4%), and sexual abuse (23.1%). Overall, 38.2% reported one ACE, 22.0% two, and 19.4% three or more. The experience of any ACE is associated with a 0.57-point increase (95% CI = 0.22-0.91) on the GAD-2 and a 0.59-point increase (95% CI = 0.30-0.88) on the PHQ-2. Any ACE is associated with a 10.0 percentage point (95% CI = 0.02, 0.18) increase in the likelihood of reporting at least mild symptoms of anxiety and a 6.6 percentage point (95% CI = 0.01-0.13) increase in the likelihood of reporting at least mild symptoms of depression. These associations are largest for individuals with 3 ACEs or more. Women face a disproportionate burden of ACEs, in terms of prevalence and cumulative exposure, and worse mental health symptoms. Conclusion: In summary, these findings highlight the importance of interventions that consider cumulative ACE exposure and adopt gender-sensitive approaches to reduce long-term mental health consequences.

Indexed as

Adverse Childhood ExperiencesAnxietyDepressionAdultCross-Sectional StudiesFemaleHumansIndonesiaMaleMiddle AgedPrevalenceSurveys and QuestionnairesYoung Adultabuseadverse childhood experiencesanxietydepressive symptomsmental health

Identifiers

PMID41450489
PMCPMC12727598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.