Evidence map›Paper›PMID 41450478›Full record

ArticleIDCases2025

Neuromelioidosis in Rajasthan: A rare and fatal manifestation of

Meenakshi Pareek, Aditi Gupta, Shailendra Prajapat, Taruna Yadav, Kumar S Abhishek, Deepak Kumar, Gopal Krishna Bohra, Mahesh Devnani, Vibhor Tak

Abstract readCase Reports
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meenakshi PareekDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, India.
Aditi GuptaDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, India.
Shailendra PrajapatDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, India.
Taruna YadavDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, India.
Kumar S AbhishekDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, India.
Deepak KumarDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Gopal Krishna BohraDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, India.
Mahesh DevnaniDepartment of Hospital Administration, All India Institute of Medical Sciences, Jodhpur, India.
Vibhor TakDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Melioidosis, an often-fatal infection caused by Case Presentation: A 65-year-old male with a background of chronic obstructive pulmonary disease (COPD) presented with prolonged fever, respiratory symptoms, and altered mental status. Neurological examination revealed increased limb tone and extensor plantar responses. Imaging revealed subcortical white matter hypodensity and multiple centrilobular nodules. Initial cerebrospinal fluid (CSF) analysis was suggestive of tubercular meningitis; however, subsequent blood and CSF cultures confirmed Discussion: Neuromelioidosis remains a diagnostic challenge due to its ability to mimic other CNS infections, particularly tuberculosis. This case underscores the critical role of microbiological confirmation in guiding treatment. While the standard treatment protocol includes an intensive phase with meropenem followed by maintenance with trimethoprim-sulfamethoxazole, delays in diagnosis significantly worsen outcomes. Conclusion: Clinicians should maintain a high index of suspicion for neuromelioidosis in patients with unexplained neurological symptoms, even in non-endemic, arid regions like Rajasthan. Timely diagnosis and targeted therapy are key to improving prognosis. This case highlights the need for greater awareness and diagnostic vigilance in atypical geographic settings.

Indexed as

Arid regionBurkholderia pseudomalleiCSFMicroabscessNeuromelioidosisRajasthan

Identifiers

PMID41450478
PMCPMC12731273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.