ReviewChemical & biomedical imaging2025
Stimulated Raman Scattering Imaging Enabled Biomarker Discovery for Precision Medicine.
Review in Chemical & biomedical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Label-Free Visualization of the Antifungal Polyene Drug, Nystatin, in Biological Membranes Using Raman Microscopy.Analytical chemistry · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular biomarkers play an essential role in accurate disease diagnosis and personalized treatment. Dysregulated metabolism is closely associated with disease development and progression. The discovery of metabolic biomarkers could remarkably promote precision diagnosis and personalized treatment. Current metabolomics approaches can profile a large number of metabolites but are primarily destructive and lack sufficient spatial resolution, which hinders quantitative measurements of the highly dynamic and heterogeneous intracellular metabolic processes. This further limits the discovery of metabolic biomarkers in these diseases. Stimulated Raman scattering (SRS) microscopy addresses these gaps by enabling label-free imaging with high sensitivity, molecular specificity, and subcellular resolution. Integrating Raman-active vibrational probes further extends this approach, allowing for real-time tracking of low-abundance biomolecules and metabolic processes. These capabilities have enabled the discovery of biomarkers for disease diagnosis. In this review, we focus on recent advancements in SRS imaging technologies and data analysis methods and their applications in biomarker discovery and precision medicine. Furthermore, future perspectives and emerging trends in this rapidly evolving research area are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.