Evidence map›Paper›PMID 41450474›Full record

ArticleChemical & biomedical imaging2025

Aggregation-Induced Emission Ionic Liquids for Bacterial Imaging, Biofilm Inhibition, and Mixed Bacterial Infection Wound Healing.

Chenxi Gao, Lei Fu, Juanjuan Wang, Yuefeng Chu, Luyao Gao, Hongdeng Qiu, Jia Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical & biomedical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenxi GaoCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Lei FuState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou Veterinary Research Institute, Lanzhou University, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.
Juanjuan WangCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Yuefeng ChuState Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou Veterinary Research Institute, Lanzhou University, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.
Luyao GaoState Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Hongdeng QiuCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.ORCID https://orcid.org/0000-0002-2702-9415
Jia ChenCAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.ORCID https://orcid.org/0000-0003-3220-4852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The excessive utilization of antibiotics escalates the susceptibility to bacterial infections in the general populace. The misuse of antibiotics and the emergence of bacterial resistance can be effectively regulated through the implementation of bacterial detection technology. Therefore, the construction of a multifunctional platform for bacterial detection and removal holds immense significance. In this research, we have effectively developed an imidazolium ionic liquid (TPE-IL) based on the tetraphenylethylene (TPE) structure with aggregation-induced emission (AIE), enabling effective bacterial imaging, biofilm inhibition, and mixed bacterial infection wound healing. TPE-IL effectively targets and penetrates bacterial surfaces via the electrostatic interactions of its imidazole groups and the hydrophobic interactions of its alkyl chains. This dual-action mechanism not only enhances fluorescence emission from the bacterial surface, enabling precise bacterial imaging, but also exhibits significant bactericidal activity. TPE-IL revealed superior antibacterial activity against both

Indexed as

Aggregation-induced emissionBacterial imagingBiofilm inhibitionIonic liquidsWound healing

Identifiers

PMID41450474
PMCPMC12728765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.