ArticleCureus2025
Management of Fracture Non-union in Children: A Literature Review With Two Case Studies.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paediatric non-union has significant implications for patients, their families, and the wider healthcare system. These implications can be clinical, such as delayed development and poor functionality, as well as psychological with respect to their overall well-being. As such, this necessitates a greater understanding and implementation of evidence-based treatment strategies to manage and prevent paediatric non-union. This study investigates the efficacy of different treatment strategies for paediatric non-union, in the form of a literature review supplemented by an analysis of two cases which presented to our local unit(s): case 1 being a four-year-old girl with a non-union of a Milch type 2 left lateral condyle fracture and case 2 being a seven-year-old boy with a non-union of a left clavicle fracture. A comprehensive literature search, on the basis of predetermined inclusion and exclusion criteria, was initially performed capturing data from 2013 to 2023 and later refreshed to the year 2025. Articles were identified using the databases PubMed, PubMed Central, Google Scholar, ResearchGate, and ScienceDirect, with an emphasis on investigating treatment efficacy for paediatric non-union. Multiple treatment options exist for effectively addressing non-union in paediatric patients, including bone grafting, ring fixation, valgus osteotomy, and the use of bone morphogenetic proteins (BMPs). Bone grafting has been the most efficacious treatment method so far, with limited complications. Of note, injury location and characteristic morphology of the non-union are the most important in determining treatment for the said non-union. Autologous bone grafting has demonstrated the best efficacy, exhibiting up to a 100% success rate in managing complex non-unions in children with few complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.