Evidence map›Paper›PMID 41450425›Full record

ArticleCureus2025

Papillary Thyroid Carcinoma Presenting as Multinodular Goiter With Possible Metastasis: A Case Study.

Aron Yunatanov, Tzipora Levitt, Tiffany K Tran, Andrew Zalot, Jonathan Gulkarov, Rafael Ilyaev, Avraham Izrailov, Stella Ilyayeva

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aron YunatanovMedicine, New York Institute of Technology (NYIT) College of Osteopathic Medicine, Old Westbury, USA.
Tzipora LevittMedicine, New York Institute of Technology (NYIT) College of Osteopathic Medicine, Old Westbury, USA.
Tiffany K TranMedicine, New York Institute of Technology (NYIT) College of Osteopathic Medicine, Old Westbury, USA.
Andrew ZalotMedicine, Hofstra University, Hempstead, USA.
Jonathan GulkarovMedicine, St. John's University, Queens, USA.
Rafael IlyaevMedicine, New York Institute of Technology (NYIT), Old Westbury, USA.
Avraham IzrailovMedicine, New York Institute of Technology (NYIT) College of Osteopathic Medicine, Old Westbury, USA.
Stella IlyayevaEndocrinology and Diabetes, Atlantic Endocrinology and Diabetes, Queens, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multinodular goiter (MNG), which may be caused by a variety of risk factors, is typically incidentally found. It is not uncommon for an incidental finding of MNG to lead to a diagnosis of papillary thyroid carcinoma (PTC); however, close monitoring for metastasis is necessary in high-risk patients. Herein, we present the case of a 71-year-old male, seemingly following a normal path of incidental discovery of MNG leading to PTC upon thyroid ultrasound and fine-needle aspiration (FNA) biopsy diagnostic exams. A total thyroidectomy was performed, with pathology confirming an aggressive tumor type (tall cell variant, T4a). Postoperative findings revealed extrathyroidal extension (ETE) with possible lung metastasis. Complications such as these highlight the importance of closely monitoring patients with a higher risk of aggressive thyroid cancer.

Indexed as

extrathyroidal extensionfine-needle aspirationlung metastasismultinodular goiterpapillary cancer of thyroid

Identifiers

PMID41450425
PMCPMC12730608

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.