ArticleCureus2025
Peripheral Nerve Stimulation to the Transverse Abdominis Plane as Therapy for Refractory Abdominal Pain: A Case Series of Two Patients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral nerve stimulation (PNS) is an emerging therapeutic intervention for chronic pain that modulates peripheral nerve activity, improving the interplay between Aβ and C fibers to reduce central sensitization and local nociceptive signaling. While the use of PNS is well supported for extremity neuropathic pain, evidence for its application in the transverse abdominis plane (TAP) remains limited. We present two patients with chronic refractory abdominal pain who underwent ultrasound-guided TAP stimulation using the SPRINT PNS (SPR Therapeutics; Cleveland, OH) system. Both experienced greater than 90% pain reduction during the 60-day stimulation period and at three-month follow-up, with one patient reporting sustained benefit beyond five months. No complications occurred other than a transient lead displacement in one case. These cases suggest that TAP PNS may be a safe and effective option for refractory abdominal pain and support further prospective evaluation of this novel application.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.