Evidence map›Paper›PMID 41450381›Full record

ArticleCureus2025

Pause the Draws: A Quality Improvement Project to Minimize Unnecessary Liver Function Tests in a Small District General Hospital.

Priyanka Kannan, Sanjana Mathew, Bethan Griffith

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Priyanka KannanMedicine, Leighton Hospital, Mid Cheshire Hospitals NHS Foundation Trust, Crewe, GBR.
Sanjana MathewMedicine, Arrowe Park Hospital, Wirral University Teaching Hospital NHS Foundation Trust, Liverpool, GBR.
Bethan GriffithAcute Medicine, Leighton Hospital, Mid Cheshire Hospitals NHS Foundation Trust, Crewe, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Blood tests are essential for diagnosis and monitoring in hospital settings, yet many are performed without clear clinical benefit. Unnecessary blood testing can negatively affect patients by prolonging hospital stays, disrupting sleep, and prompting further investigations that may not be needed, while also adding avoidable financial costs and carbon emissions. This quality improvement project focused on reducing inappropriate liver function tests (LFTs) in two medical wards, following the Royal College of Pathology (RCPath) guidelines, with the aim of halving the proportion of inappropriate tests. Our initial audit identified that 28% of LFTs performed on the wards were unnecessary, demonstrating a clear opportunity for improvement. Methods The extent and causes of unnecessary LFTs were identified across two medical wards. Following the RCPath guidelines, any LFT repeated within 72 hours of a previous test was considered inappropriate unless an exclusion criterion applied. Interventions were implemented over four Plan-Do-Study-Act (PDSA) cycles. Weekly data were collected on the total and inappropriate number of LFTs for every patient present on the wards on Fridays. For each inappropriate LFT, the request information was reviewed to assess the rationale and inform subsequent PDSA cycles. Results Across the four PDSA cycles, inappropriate LFTs decreased from 72 out of 257 (28.0%) to 18 out of 98 (18.4%). The weekly LFT carbon footprint decreased from 263.34 kgCO₂e to 83.2 kgCO₂e. The weekly cost of unnecessary LFTs was reduced from £140.79 to £44.46. Conclusions The reduction of inappropriate LFTs yielded measurable clinical, environmental, and financial benefits. Patients avoided unnecessary blood tests that could complicate or prolong their admissions. Cost savings were demonstrated, and the hospital's carbon footprint was reduced. The project's impact, achieved through simple and practical interventions, highlights that physician education is central to optimizing blood testing.

Indexed as

carbon footprintcost savingsenvironmentliver function testquality improvementsustainable healthcareunnecessary blood tests

Identifiers

PMID41450381
PMCPMC12737422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.