Evidence map›Paper›PMID 41450361›Full record

ArticleCureus2025

A Rare Case of a Brain Abscess With a History of Penicillin Allergy.

Ryuichi Hirano

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ryuichi HiranoPharmacy, Sapporo Azabu Neurosurgical Hospital, Sapporo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The administration of β-lactam antibiotics is the standard treatment for brain abscesses. However, there are no detailed case reports of brain abscesses with a history of allergy to β-lactam antibiotics. Here, we present the case of a patient with a penicillin allergy who underwent successful treatment for a brain abscess without the recurrence of anaphylaxis symptoms. A 91-year-old man was admitted with a brain abscess. β-Lactam antibiotics were not considered to be suitable because the patient had previously developed anaphylaxis symptoms to penicillin antibiotics. Due to poor oral hygiene, anaerobic bacteria were suspected as the underlying cause of the brain abscess. Intravenous metronidazole (MNZ) therapy was initiated after intracerebral drainage.

Indexed as

brain abscessfusobacterium necrophorummetronidazoleodontogenic infectionpenicillin allergy

Identifiers

PMID41450361
PMCPMC12729450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.