Evidence map›Paper›PMID 41450355›Full record

ArticleCureus2025

Clinical Profile, Endoscopic Findings, and Outcomes Among Inpatients With Upper Gastrointestinal Bleeding in a United Kingdom District General Hospital.

Mansur F Mohammed, Rajesh K Gurunathan, Nourhan N Eltanikhy, Pavithra Dhanasekaran

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mansur F MohammedGastroenterology, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent, GBR.
Rajesh K GurunathanAcute Internal Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent, GBR.
Nourhan N EltanikhyAcute Internal Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent, GBR.
Pavithra DhanasekaranAcute Internal Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Burton-on-Trent, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Acute upper gastrointestinal bleeding (AUGIB) is a medical emergency associated with significant morbidity and mortality. Prognosis and management are typically determined by the patient's clinical features and findings on endoscopy. Objective This study aimed to evaluate the demographic characteristics, risk stratification, endoscopic findings, and therapeutic interventions in patients presenting with AUGIB at Queens Hospital, Burton, United Kingdom, in 2024. Methods A retrospective analysis was performed of all inpatients who underwent upper gastrointestinal endoscopy for hematemesis and/or melena from January to December 2024. Data on demographics, Glasgow-Blatchford Score (GBS), hemodynamic status, endoscopic diagnoses, interventions, and outcomes were obtained from electronic medical records and analyzed using SPSS Version 23 (IBM Corp., Armonk, NY, USA). Results Sixty-four patients (mean age 72.1±15.8; 71% male) were included. Nonvariceal bleeding accounted for 92% of cases, with duodenal ulcers (17%) and gastric ulcers (11%) as leading etiologies. All patients were risk-assessed using the GBS on admission. Twenty-five percent of patients with nonvariceal bleeding required therapeutic endoscopy, primarily using dual or triple modalities. Variceal bleeds (8%) were managed with terlipressin, antibiotics, and band ligation based on endoscopic grade. Re-bleeding occurred in 3.1% of patients, necessitating further interventions. Conclusion AUGIB predominantly affected elderly males, with nonvariceal etiologies, particularly peptic ulcers, being most common. Universal risk stratification and timely endoscopic intervention in line with best practices helped improve outcomes. The study recorded a low re-bleeding rate.

Indexed as

acute upper gastrointestinal bleedingendoscopygastrointestinal bleedinggastrointestinal hemorrhagehematemesisnon-variceal bleedingrisk stratificationupper gi bleedvariceal bleeding

Identifiers

PMID41450355
PMCPMC12729445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.