Evidence map›Paper›PMID 41450340›Full record

ArticleCardiovascular endocrinology & metabolism2026

Pulse wave velocity is elevated in people with serious mental illness with vascular age advanced in two-thirds of individuals.

Adrian H Heald, Sangeeth Veluchamy, Karen Barchetti, Magdalena Nasadowska, Aran Gillespie, Boris Mankovsky, Gibson J Martin, Simon G Anderson, Michael Crawford, Pierre Boutouyrie

Abstract read
In one paragraph

Article in Cardiovascular endocrinology & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adrian H HealdSalford Royal Hospital, Salford.
Sangeeth VeluchamySalford Royal Hospital, Salford.
Karen BarchettiHôpital Européen Georges-Pompidou, Universitye Paris Cite, Paris, France.
Magdalena NasadowskaPrestwich Hospital, Greater Manchester, UK.
Aran GillespiePrestwich Hospital, Greater Manchester, UK.
Boris MankovskyNational Medical Academy for Postgraduate Education, Kyiv, Ukraine.
Gibson J MartinSalford Royal Hospital, Salford.
Simon G AndersonCaribbean Institute for Health Research, The University of the West Indies, Kingston, Jamaica.
Michael CrawfordPrestwich Hospital, Greater Manchester, UK.
Pierre BoutouyrieHôpital Européen Georges-Pompidou, Universitye Paris Cite, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: People with serious mental illness (SMI) have a higher than average cardiovascular event rate/shortened life expectancy by up to 20 years. The higher incidence of cardiovascular events is not sufficiently accounted for by traditional risk factors. It has been established that aortic stiffness assessed with pulse wave velocity (PWV) correlates with vascular inflammation/increased risk for cardiovascular events. Methods: We measured PWV/central blood pressure by photoplethysmography in 15 long-term psychiatry inpatients on a specialist inpatient ward, during a 5-min period of rest with the pOpmètre. The pOpmètre is a class IIa medical device, noninvasive and nonoperator dependent. Results: Mean age was 59.2 years (range: 26-79 years). Mean body (SD) BMI was 33.1 (7.7) kg/m Conclusion: We describe differences in major arterial vessel health that may account for some of the excess cardiovascular event rate/excess mortality in people with SMI.

Indexed as

central blood pressurepulse wave velocityserious mental illnessvascular age

Identifiers

PMID41450340
PMCPMC12727390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.