Evidence map›Paper›PMID 41450201›Full record

ArticleBioinformatics (Oxford, England)2026

BPSS: a Nextflow pipeline for Bacterial Peptide Sequence Selection to detect protein diversity.

Sylvère Bastien, Pauline François, Sara Moussadeq, Jérôme Lemoine, Karen Moreau, François Vandenesch

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylvère BastienCIRI, Center for Integrative Research in Infectious Diseases and Immunology, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, 69007, France.ORCID 0000-0002-3687-8646
Pauline FrançoisCIRI, Center for Integrative Research in Infectious Diseases and Immunology, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, 69007, France.
Sara MoussadeqCIRI, Center for Integrative Research in Infectious Diseases and Immunology, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, 69007, France.
Jérôme LemoineUniversité de Lyon, CNRS, Université Claude Bernard Lyon 1, Institut des Sciences Analytiques, UMR 5280, Villeurbanne, 69100, France.
Karen MoreauCIRI, Center for Integrative Research in Infectious Diseases and Immunology, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, 69007, France.
François VandeneschCIRI, Center for Integrative Research in Infectious Diseases and Immunology, Université de Lyon, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, 69007, France.ORCID 0000-0001-9412-7106

Funding

Agence Nationale de la Recherche ANR-18-RHUS-0013
6 · The paper itself

Abstract

motivationSequence variability can be extremely high, particularly in bacteria due to the rapid accumulation of mutations linked to their high replication rate and environmental selection pressure, which often favors diversifying selection. For most species, there are no automated, computationally efficient tools available for constructing a nonredundant database covering the allelic variability of target proteins.

resultsWe have thus developed Bacterial Peptide Sequence Selection, a Nextflow pipeline to define a minimal list of peptide sequences for detecting all variants of a protein of interest. AVAILABILITY AND IMPLEMENTATION: All the code and containers used are freely available on Gitlab from https://gitbio.ens-lyon.fr/ciri/stapath/bpss or on Zenodo (10.5281/zenodo.16894981) under GPLv3 open-source license and DockerHub platform from https://hub.docker.com/u/stapath.

Indexed as

Bacterial ProteinsPeptidesSequence Analysis, ProteinSoftwareAmino Acid SequenceDatabases, ProteinGenetic VariationBacterial ProteinsPeptides

Identifiers

PMID41450201
PMCPMC12797209

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.