Evidence map›Paper›PMID 41450199›Full record

ArticleJournal of periodontology2026

Predicting peri-implantitis incidence and implant failure via risk-assessment and prognostication tools: A validation study.

Muhammad H A Saleh, Era Kakar, Giuseppe Troiano, Hamzeh Almashni, Jonathan Misch, Fariba Esperouz, Shahad Alhazmi, Hom-Lay Wang, Zoltán Baráth, Istvan A Urban

Abstract readValidation Study
In one paragraph

Article in Journal of periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad H A SalehDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0001-5067-7317
Era KakarDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0009-0006-4823-9231
Giuseppe TroianoDepartment of Medicine and Surgery, University LUM, Casamassima, Italy.ORCID https://orcid.org/0000-0001-5647-4414
Hamzeh AlmashniDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0009-0001-0804-2729
Jonathan MischDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Fariba EsperouzDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.ORCID https://orcid.org/0009-0008-1820-899X
Shahad AlhazmiDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0009-0008-2112-2804
Hom-Lay WangDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-4238-1799
Zoltán BaráthDepartment of Periodontology, University of Szeged, Szeged, Hungary.ORCID https://orcid.org/0000-0003-0636-6313
Istvan A UrbanDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-9368-4047

Funding

Department of Periodontics and Oral MedicineGraduate Periodontics research fundUniversity of Michigan School of Dentistry
6 · The paper itself

Abstract

backgroundIdentifying individuals at high risk for developing peri-implantitis (PI) and then determining the prognosis for implants with PI is crucial for treatment planning.

methodsThis study longitudinally followed implants from implant placement retrospectively. The peri-implant disease risk assessment (IDRA) tool was applied, and the performance of the Kwok and Caton (KC) implant prognostication tool was compared with that of a new tool based on the frequency of progressive bone loss (PBL). The predictive accuracy of IDRA, PBL, and KC was evaluated at the corresponding time points (T1-T5). Fisher's exact test was used to evaluate categorical variables, and the Mann-Whitney test was used to evaluate continuous variables. Multiple regression models were built to correlate the occurrence of peri-implantitis and implant survival. The study followed the OHstat and TRIPOD guidelines for reporting.

results146 dental implants in 87 patients were included (age = 63.19 ± 11.38 years). IDRA classified the implants as 85.62% high-, 14.38% moderate-, and 0% low-risk. The KC scores showed 7.53% of implants with a favorable-, 65.07% with a questionable-, and 27.4% with an unfavorable prognosis. IDRA showed limited predictive power with an AUC of 0.533 (95% CI: 0.477-0.590). The KC tool performed much better, where a score of 2 had an AUC of 0.8321 (95% CI: 0.7257-0.9386). PBL yielded a moderate but consistent effectiveness with an AUC of 0.7697 (95% CI: 0.593-0.9463).

conclusionThe KC and PBL prognostication tools exhibited good predictive capability for implant survival, while the IDRA tool demonstrated marginal efficacy in predicting the incidence of peri-implantitis. PLAIN LANGUAGE SUMMARY: In this study, we followed 87 patients with 146 implants over time to test how well different tools can predict implant health and survival. We tested three tools, IDRA for predicting peri-implantitis, the KC system, and a new tool based on progressive bone loss for predicting implant survival. After 2 years with the implant crowns in place, we checked for cases of peri-implantitis. At the final follow-up (up to 8 years), the implant survival was assessed. We found that IDRA was not effective in predicting which implants developed peri-implantitis, even in high- and moderate-risk implants. In contrast, the KC tool was much more accurate, predicting implant survival in about 80% of cases. The PBL tool was also good in predicting implant survival, but slightly less accurate than the KC tool.

Indexed as

Dental ImplantsDental Restoration FailurePeri-ImplantitisAgedAlveolar Bone LossFemaleHumansIncidenceLongitudinal StudiesMiddle AgedPrognosisRetrospective StudiesRisk AssessmentDental Implantsdental implantsimplant survivalperi‐implantitisprognosisretrospective studiesrisk assessment

Identifiers

PMID41450199
PMCPMC13502412

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.