Evidence map›Paper›PMID 41450105›Full record

ArticleClinical and experimental pediatrics2026

Improvements in obesity-related measures among Asian patients with severe obesity following a structured lifestyle intervention.

Pei-Shan Chen, Shu-Mei Tsai, Chih-Hsuan Chang, Hui-Ru Yang, Yen-Ju Huang, Hsiang-Yin Liu, Kai-Chi Chang, Huey-Ling Chen

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Article in Clinical and experimental pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Pei-Shan ChenDivision of Physical Therapy, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Shu-Mei TsaiDepartment of Dietetics, National Taiwan University Hospital, Taipei, Taiwan.
Chih-Hsuan ChangDepartment of Clinical Psychology Center, National Taiwan University Hospital, Taipei, Taiwan.
Hui-Ru YangDepartment of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Yen-Ju HuangDivision of Physical Therapy, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Hsiang-Yin LiuDivision of Physical Therapy, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Kai-Chi ChangDepartment of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Huey-Ling ChenDepartment of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.

Funding

National Taiwan University Hospital 108-S4327
6 · The paper itself

Abstract

backgroundThe rising prevalence of severe obesity among children and adolescents poses a major public health challenge. PURPOSE: In this study, we examined the differences in body composition and physical fitness between obese and severely obese Asian youth and evaluated their responses to a customized lifestyle intervention.

methodsA total of 136 overweight and obese participants (mean age, 11.5±3.0 years) were enrolled in an individualized lifestyle modification program. The participants were stratified by obesity severity, with severe obesity defined as a body mass index (BMI)-for-age ≥120% of the 95th percentile. Body composition and physical fitness were assessed at baseline and after 3 interventional stages. The results were compared between the severely obese group and nonseverely obese group, and the relationships between the changes were analyzed.

resultsAmong the obese participants, 46% met the criteria for severe obesity. At baseline, those with severe obesity demonstrated a lower performance percentile in the 1-minute sit-up test (22.1±25.2 vs. 47.9±28.0, P=0.002) and the standing long jump (8.5±14.6 vs. 26.8±23.2, P= 0.003) than their nonseverely obese peers. Participants in both groups showed significant reductions in body fat percentage and preserved skeletal muscle mass after the intervention. Those in the severely obese group achieved greater reductions in weight, BMI, BMI z score, and fat mass, particularly during the first 2 interventional stages, indicating a stronger response to the program.

conclusionThe severely obese youth showed poorer baseline physical fitness levels but greater improvements in key obesity-related measures following the lifestyle interventions. These findings highlight the potential benefits of early targeted interventions for this high-risk group.

Indexed as

LifestyleObesity managementPediatric obesityPhysical fitness

Identifiers

PMID41450105
PMCPMC12963938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.