Evidence map›Paper›PMID 41449785›Full record

ArticleBritish journal of haematology2026

T-cell immunomodulation occurs with different time kinetics during acalabrutinib and zanubrutinib therapy in chronic lymphocytic leukaemia.

Maria L Andersson, Olina Lind, Kia Heimersson, Anna Berglöf, Teresa Del Peso Santos, Lucía Peña-Pérez, Qing Wang, Tom A Mulder, Rula Zain, Robert Månsson and 4 more

Abstract read
In one paragraph

Article in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maria L AnderssonDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0005-3957-8680
Olina LindDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0009-3477-1480
Kia HeimerssonDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0005-0375-5139
Anna BerglöfDepartment of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-5443-968X
Teresa Del Peso SantosDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Lucía Peña-PérezCentre for Inherited Metabolic Diseases, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-5044-7754
Qing WangDepartment of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-9570-4411
Tom A MulderDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-6554-3263
Rula ZainDepartment of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8327-846X
Robert MånssonDepartment of Laboratory Medicine, Division of Clinical Immunology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-0738-0328
Richard RosenquistDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0211-8788
C I Edvard SmithDepartment of Laboratory Medicine, Division of Biomolecular and Cellular Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-1907-3392
Anders ÖsterborgDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6489-4865
Marzia PalmaDepartment of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4287-3179

Funding

King Gustav V Jubilee FundThe Center for Innovative Medicine (CIMED) FoUI-999363The Stockholm County Council FoUI-960534The Stockholm County Council FoUI-97465The Stockholm County Council RS2022-067The Swedish Blood Cancer AssociationThe Swedish Cancer Foundation 222188Fk01HThe Swedish Cancer Foundation 243388Pj01HThe Swedish Research CouncilUnrestricted Research Grants by BeOne Medicines and AstraZeneca (MP)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BTK inhibitorschronic lymphocytic LeukaemiaT cells

Identifiers

PMID41449785
PMCPMC12995531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.