Evidence map›Paper›PMID 41449428›Full record

Trial reportEuropean journal of medical research2025

Transnasal humidified rapid insufflation ventilatory exchange versus conventional facemask breathing for preoxygenation during anesthesia induction in TBI surgery: a randomized controlled trial.

Xiaoping Chen, Chen Yang, Yue Zhao, Ju Gao, Yali Ge, Yang Zhang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoping ChenClinical Medical College, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Chen YangDepartment of Anesthesiology, Institute of Anesthesia, Emergency and Critical Care, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 98 Nantong West Road Guangling District, Yangzhou, 225002, Jiangsu, China.
Yue ZhaoDepartment of Anesthesiology, Institute of Anesthesia, Emergency and Critical Care, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 98 Nantong West Road Guangling District, Yangzhou, 225002, Jiangsu, China.
Ju GaoDepartment of Anesthesiology, Institute of Anesthesia, Emergency and Critical Care, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 98 Nantong West Road Guangling District, Yangzhou, 225002, Jiangsu, China.
Yali GeClinical Medical College, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Yang ZhangDepartment of Anesthesiology, Institute of Anesthesia, Emergency and Critical Care, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 98 Nantong West Road Guangling District, Yangzhou, 225002, Jiangsu, China. 18051063040@yzu.edu.cn.

Funding

National Natural Science Foundation of China 82172190
6 · The paper itself

Abstract

objectiveTo assess the effect of transnasal humidified rapid insufflation ventilatory exchange (THRIVE) on regional cerebral oxygen saturation (rScO

methodsIn this prospective randomized trial, 63 TBI patients undergoing emergency intracranial hematoma removal were allocated to conventional mask ventilation group (n = 32; 8 L/min O2, FiO2 1.00) or THRIVE group (n = 31; 30-50 L/min O2, FiO2 1.00). Outcomes included rScO2, PaO2, PaCO2, hypoxemia incidence (SpO2 < 95%), end-tidal CO2 (PETCO2), and Glasgow Outcome Scale (GOS) at discharge.

resultsAfter 10-min preoxygenation, the THRIVE group exhibited higher rScO

conclusionTHRIVE could significantly increase rScO

Indexed as

Anesthesia, GeneralBrain Injuries, TraumaticInsufflationRespiration, ArtificialAdultFemaleHumansMaleMiddle AgedOxygenOxygen SaturationProspective StudiesOxygenCross-sectional areaGlasgow Outcome ScaleInduction of general anesthesiaOptic nerve sheath diameterRegional cerebral oxygen saturationTransnasal humidified rapid insufflation ventilatory exchangeTraumatic brain injury

Identifiers

PMID41449428
PMCPMC12849737

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.