Evidence map›Paper›PMID 41448815›Full record

ArticleFamily medicine and community health2025

Burden and risk factors of mental and substance use disorders among children aged 5-14 in Asia from 1990 to 2021: results from the Global Burden of Disease study.

Yanyan Wang, Huifang Yang, Yizhen Wu, Jiahui Li, Chikyu Tsin, Shuyang Ren, Jun Zhang, Yuling Qiao, Xiwang Fan

Abstract read
In one paragraph

Article in Family medicine and community health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanyan WangClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.ORCID 0009-0002-1903-182X
Huifang YangClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.ORCID 0009-0003-8530-5048
Yizhen WuClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.ORCID 0009-0001-5007-0336
Jiahui LiClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.
Chikyu TsinClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.ORCID 0009-0000-1435-3198
Shuyang RenClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China.ORCID 0009-0004-6051-7148
Jun ZhangGongli Hospital, Pudong New Area, Shanghai, China.ORCID 0009-0006-7007-7398
Yuling QiaoThe New Bund School Attached to No.2 High School of ECNU, Shanghai, China.ORCID 0009-0006-3165-9352
Xiwang FanClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai, China fanxiwang2020@163.com.ORCID 0000-0003-4180-0496

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

‌

objectiveTo analyse trends in mental and substance use disorders among Asian children aged 5-14 years, identify key risk factors (eg, bullying, abuse, lead exposure) and compare gender/age disparities using Global Burden of Disease (GBD) 2021 data. ‌

designCross-sectional analysis of the GBD 2021 database, focusing on prevalence, disability-adjusted life years (DALYs) and risk factor associations. ‌

settingPopulation-based study across Asian countries, examining the burdens of mental health, especially substance use disorders in high-prevalence regions. ‌

participantsChildren aged 5-14 years in Asia, with gender-stratified subgroups (boys vs girls). ‌

resultAnxiety, conduct disorders and autism were primary contributors to mental health burdens. Substance use disorders, though less prevalent, rose notably among boys. Girls showed higher burdens of anxiety/depressive disorders. Bullying and childhood abuse were strongly linked to these conditions. Gender disparities in DALYs highlighted boys' vulnerability to substance use and girls to internalising disorders. ‌

conclusionUrgent, region-specific interventions are needed to address bullying, lead exposure and abuse, with gender-sensitive strategies. The study calls for targeted research and policies to mitigate rising mental health challenges in Asian children.

Indexed as

Mental DisordersSubstance-Related DisordersAdolescentAsiaBullyingChildChild, PreschoolCross-Sectional StudiesDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansMalePrevalenceRisk FactorsAdolescent HealthDrug CostsMental HealthPsychology, Adolescent

Identifiers

PMID41448815
PMCPMC12742091

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.