ArticleRMD open2025
Novel vascular damage markers in SLE: insights from carotid colour Doppler ultrasound and aortic oscillometry in the LUPCARD cohort.
Article in RMD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Macrovascular damage in polymyalgia rheumatica: integrated vascular phenotyping in the POLYMYACARD cohort.Arthritis research & therapy · 2026Article
- Serum lipidomic and metabolomic signatures link epicardial adipose tissue to cardiovascular diseases in SLE: a post-hoc analysis.Lupus science & medicine · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess for the first time a combination of new and established markers of macrovascular damage in patients with systemic lupus erythematosus (SLE) using oscillometry and greyscale/colour Doppler ultrasound (GSUS/CDUS) and, additionally, to explore associations of these markers with traditional cardiovascular (CV) risk factors and patient and disease characteristics.
methodsCDUS was used to assess arterial compliance markers, such as the Resistance-Index (RI) and Pulsatility-Index (PI) of the common (CCA) and internal carotid artery (ICA) in SLE patients and healthy controls. Carotid intima-media thickness (cIMT), atherosclerotic plaque and total calcification area were evaluated by GSUS. Aortic stiffness was measured by carotid-femoral pulse wave velocity (cfPWV).
resultsWe recruited
conclusionsIn the first study of CV surrogate markers in SLE combining oscillometry and carotid CDUS/GSUS, patients showed increased carotid pulsatility and resistance compared with controls. Furthermore, several patient-related and disease-related factors were identified as angiopathy predictors. These results suggest that combined evaluation of CV surrogate markers may help detect subclinical organ damage and improve CV-risk classification in SLE.
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