ArticleAnalytical chemistry2026
Real-Time Identification and Quantification of Per- and Polyfluoroalkyl Substances Using High-Resolution Time-of-Flight Chemical Ionization Mass Spectrometry with Positive Reagent Ions.
Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
Funding
Abstract
Per- and polyfluoroalkyl substances (PFAS) are emerging pollutants of concern, primarily due to their terminal degradation products, which exhibit environmental persistence and mobility. Several groups of PFAS, including hydrofluoroolefins (HFOs), perfluoro olefins (PFOs), perfluoro vinyl ethers (PVEs), and hydrofluoroalkanes (HF-alkanes), are volatile and reside predominantly in the gas phase. PFAS such as HFOs, PFOs, and PVEs are considered reactive and may generate short-chain degradation products that persist in the environment. Despite the importance of these gaseous PFAS, there is a lack of analytical techniques capable of providing high-resolution temporal measurements of potential precursors to terminal degradation products. This study presents the first real-time method for detecting and quantifying atmospheric HFOs, PFOs, PVEs, and HF-alkanes using a high-resolution chemical ionization mass spectrometer (HR-CIMS). Using NO
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