Evidence map›Paper›PMID 41447649›Full record

ArticleEuropean journal of breast health2025

Sentinel Lymph Node Biopsy for Breast Cancer in North Africa: A Retrospective Analysis of Feasibility, Safety, and Morbidity Reduction in a Real-World Setting.

Aziz Belkhodja, Yasmine Chiba, Lamia Zaabar, Wissal Jaafar, Medemagh Malak, Mehdi Bouassida, Cherifa Ben Sethom, Nahed Khalifa, Manel Mabrouk, Aida Mhiri and 1 more

Abstract read
In one paragraph

Article in European journal of breast health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aziz BelkhodjaDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.
Yasmine ChibaDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.
Lamia ZaabarDepartment of Nuclear Medicine, Salah Azaeiz Institute, Tunis, Tunisia.
Wissal JaafarDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.ORCID 0009-0007-5044-9913
Medemagh MalakDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.ORCID 0009-0009-1278-5777
Mehdi BouassidaDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.
Cherifa Ben SethomDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.
Nahed KhalifaDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.ORCID 0009-0004-8360-4543
Manel MabroukDepartment of Oncology, Bougatfa University Hospital, Bizerte, Tunisia.
Aida MhiriDepartment of Nuclear Medicine, Salah Azaeiz Institute, Tunis, Tunisia.
Mechaal MouraliDepartment of Gynecology and Obstetrics, University Hospital of Bizerte, Bizerte, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Conventional axillary lymph node dissection (ALND) carries significant morbidity in breast cancer surgery. Sentinel lymph node biopsy (SLNB) offers a less invasive alternative but lacks validation in resource-constrained environments. To compare postoperative morbidity between SLNB and ALND in breast cancer and assess SLNB feasibility. Materials and Methods: A retrospective study was conducted at the Mother-Child Department of Bizerte, Tunisia (January 2022-August 2024). Patients with early-stage breast cancer undergoing SLNB or ALND were included. Primary outcomes were: lymphedema, lymphocele, pain [visual analog scale (VAS)], hemoglobin drop, and length of hospital stay. Statistical analyses were performed using SPSS v26.0. The Student's t-test was used for normally distributed quantitative variables, the Mann-Whitney U test for non-normally distributed variables, and Fisher's exact test for categorical variables with small sample sizes. Normality was assessed using the Shapiro-Wilk test. Results: Among the 64 included patients, SLNB ( Conclusion: SLNB significantly reduces postoperative morbidity compared with ALND and is feasible in this resource-limited North African setting. Our findings support its integration into routine breast cancer surgery as a safe and effective alternative to axillary dissection.

Indexed as

axillary lymphadenectomybreast cancerfeasibilitylymphedemapostoperative morbiditySentinel lymph node biopsy

Identifiers

PMID41447649
PMCPMC12740283

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.