Evidence map›Paper›PMID 41447022›Full record

ReviewTurkish journal of ophthalmology2025

Decision-Making in Keratoprosthesis: Navigating Device Selection in Complex Ocular Scenarios.

Shweta Agarwal, Varsha Bhambhani, Mugundhan Rajarajan, James Chodosh

Abstract readReview
In one paragraph

Review in Turkish journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shweta AgarwalCJ Shah Cornea Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.ORCID 0000-0002-7903-9500
Varsha BhambhaniCJ Shah Cornea Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.ORCID 0009-0008-9354-6075
Mugundhan RajarajanCJ Shah Cornea Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.ORCID 0009-0009-3825-9695
James ChodoshUniversity of New Mexico School of Medicine, Albuquerque, New Mexico, USA.ORCID 0000-0002-7463-1599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratoprosthesis (KPro) implantation serves as a last resort for visual rehabilitation in patients with end-stage bilateral corneal blindness, particularly when conventional corneal transplantation is no longer viable. Advances in biomaterials and refinements in prosthetic design have significantly enhanced anatomical retention and visual outcomes. Among the various types available, the Boston type 1 and 2 devices and the modified osteo-odonto-KPro remain the most widely utilized globally. This review aims to support comprehensive clinical decision-making by providing an in-depth overview of the design characteristics, surgical considerations, and postoperative care protocols associated with the most widely used KPro devices. In addition, we discuss a broad range of influencing factors, including the status of the ocular surface, eyelid anatomy, tear film adequacy, underlying systemic or autoimmune diseases, and patient-related logistical and socioeconomic concerns. Special emphasis is placed on the importance of preoperative evaluation and counselling and the role of a multidisciplinary approach in achieving successful long-term outcomes. Drawing on current evidence and clinical experience, we propose a practical decision-making algorithm to aid ophthalmologists in selecting the most appropriate KPro tailored to individual patient profiles.

Indexed as

Clinical Decision-MakingCorneaCorneal DiseasesDecision MakingProstheses and ImplantsProsthesis ImplantationVisual AcuityHumansProsthesis DesignBoston type 1Boston type 2Keratoprosthesismodified osteo-odonto-keratoprosthesisMOOKPtibial keratoprosthesis

Identifiers

PMID41447022
PMCPMC12740060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.