ArticleFrontiers in medicine2025
Clinical characteristics and outcomes of liver abscesses: a 12-year retrospective analysis from a tertiary care center in the United Arab Emirates.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
Background: Liver abscesses are a cause of morbidity worldwide and their outcomes can vary remarkably in various regions of the world. In the United Arab Emirates (UAE) the clinical picture of liver abscesses is not fully understood. We aimed to fill this gap by analyzing the clinical features, microbiology, and outcomes for patients with liver abscess over a 12-year period. Methods: We conducted a retrospective observational study of all adult patients (≥18 years) with confirmed diagnosis of liver abscess at Tawam Hospital, Al Ain, UAE, from January 2012 to January 2024. Electronic medical records were reviewed to extract demographic, clinical, laboratory, radiological, and microbiological data. Patients were then classified as either having pyogenic liver abscess (PLA) or amoebic liver abscess (ALA). Statistical analyses were performed to identify predictors of morbidity and mortality. Results: Of 158 patients screened, 79 had confirmed liver abscesses (71 pyogenic, 8 amoebic). The mean age was 56.8 ± 16.2 years, with male predominance (65.8%). The commonest clinical findings were abdominal pain (73.4%), fever (68.4%), and nausea/vomiting (45.6%). Diabetes mellitus was found in 35.4% of patients, while malignancy was identified in 30.4%. Conclusion: The overwhelming majority of patients with liver abscesses at high-risk for complications respond favorably to antimicrobial therapy. However, the most striking finding was the unexpectedly observed mortality associated with
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