ArticleFrontiers in medicine2025
The effect of remimazolam versus conventional anesthesia on postoperative delirium in frail patients: a prospective, controlled cohort study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of Remimazolam on Postoperative Delirium in Elderly Surgical Patients: A Critical Review of Pharmacological Mechanisms and Clinical Evidence.Drug design, development and therapy · 2026Review
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Authors and funding
5 authors.
Funding
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Abstract
Background: Frail elderly patients are at high risk for postoperative delirium (POD), a serious complication associated with poor outcomes. The choice of anesthetic agent may represent a modifiable risk factor. This study aimed to compare the effect of anesthesia involving remimazolam versus conventional general anesthesia without remimazolam on the incidence of POD in this vulnerable population. Methods: We enrolled frail elderly patients (defined as Clinical Frailty Scale ≥ 5) scheduled for elective non-cardiac surgery. Patients received either anesthesia involving remimazolam (R group, Results: Between June 2024 and June 2025, a total of 606 patients were enrolled and analyzed (R group: Conclusion: In this cohort of frail elderly patients, the use of remimazolam for general anesthesia was associated with a lower incidence of postoperative delirium compared to conventional anesthesia. This choice represents a promising, modifiable strategy for improving neurological outcomes in this high-risk group.
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