Evidence map›Paper›PMID 41446741›Full record

ArticleiScience2025

CCL19-armed recombinant influenza virus inhibited colorectal cancer growth by remodeling tumor microenvironment.

Xia Ou, Yunxin Xia, Zhongyue Fang, Kai Yang, Guangtao Yang, Junying Wang, Yiyong Duan, Xiahui Yang, Bing Yang, Ze Liu and 1 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xia OuBasic Medical School, Kunming University of Science and Technology, Kunming 67800, P.R. China.
Yunxin XiaBasic Medical School, Kunming University of Science and Technology, Kunming 67800, P.R. China.
Zhongyue FangBasic Medical School, Kunming University of Science and Technology, Kunming 67800, P.R. China.
Kai YangBasic Medical School, Kunming University of Science and Technology, Kunming 67800, P.R. China.
Guangtao YangBasic Medical School, Kunming University of Science and Technology, Kunming 67800, P.R. China.
Junying WangLibrary, Kunming Medical University, Kunming 678000, P.R. China.
Yiyong DuanLijiang People's Hospital, Lijiang 674100, P.R. China.
Xiahui YangLijiang People's Hospital, Lijiang 674100, P.R. China.
Bing YangSchool of Basic Medical Science, Tianjin Medical University, Tianjin 300400, P.R. China.
Ze LiuBio-X Center for Interdisciplinary Innovation, Yunnan University, Kunming 678000, P.R. China.
Jihong ZhangBasic Medical School, Kunming University of Science and Technology, Kunming 67800, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The "cold" tumor microenvironment (TME) impaired colorectal cancer (CRC) immunotherapy efficacy, while oncolytic viruses (OVs) could "heat" TME and stimulate anti-tumor immunity. Here, it rescued

Indexed as

CancerImmune systemImmunology specialty

Identifiers

PMID41446741
PMCPMC12723135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.